Article
In children with autoimmune thyroiditis CTLA4 and FCRL3 genes--but not PTPN22--are overexpressed when compared to adults.
Neuro endocrinology letters - 1 Jan 2016
Wojciechowska-Durczynska Katarzyna, Krawczyk-Rusiecka Kinga, Zygmunt Arkadiusz, Stawerska Renata, Lewinski Andrzej
Abstract excerpt
BACKGROUND: Numerous genetic studies revealed several susceptibility genes of autoimmune thyroid diseases (AITD), including CTLA4, PTPN22 and FCRL3. These immune-modulating genes are involved in genetic background of AITD among children and adult patients. However, possible age-related differences in overexpression of these genes remain unclear. PURPOSE: The goal of this single centre cohort study was evaluation...
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