Article
Fine-mapping of two differentiated thyroid carcinoma susceptibility loci at 9q22.33 and 14q13.3 detects novel candidate functional SNPs in Europeans from metropolitan France and Melanesians from New Caledonia.
International journal of cancer - 1 Aug 2016
Tcheandjieu Catherine, Lesueur Fabienne, Sanchez Marie, Baron-Dubourdieu Dominique, Guizard Anne-Valerie, Mulot Claire, Laurent-Puig Pierre, Schvartz Claire, Truong Therese, Guenel Pascal
Abstract excerpt
Incidence of differentiated thyroid carcinoma varies considerably between countries and ethnic groups, with particularly high incidence rates in Melanesians of New Caledonia. Differentiated thyroid cancer (DTC) has a familial relative risk higher than other cancers, highlighting the contribution of inherited factors to the disease. Recently, genome-wide association studies (GWAS) identified several DTC...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.