Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations.

doi:10.1002/ijc.29557

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Article

Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations.

International journal of cancer - 15 Oct 2015

Mancikova Veronika, Cruz Raquel, Inglada-Pérez Lucía, Fernández-Rozadilla Ceres, Landa Iñigo, Cameselle-Teijeiro José, Celeiro Catuxa, Pastor Susana, Velázquez Antonia, Marcos Ricard, Andía Victor, Álvarez-Escolá Cristina, Meoro Amparo, Schiavi Francesca, Opocher Giuseppe, Quintela Inés, Ansede-Bermejo Juan, Ruiz-Ponte Clara, Santisteban Pilar, Robledo Mercedes, Carracedo Angel

Abstract excerpt

Thyroid cancer is the most heritable cancer of all those not displaying typical Mendelian inheritance. However, most of the genetic factors that would explain the high heritability remain unknown. Our aim was to identify additional common genetic variants associated with susceptibility to this disease. In order to do so, we performed a genome-wide association study in a series of 398 cases and 502 controls from...

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PMID: 25855579
DOI: 10.1002/ijc.29557

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FOXE1

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