Article
Dynamics of the T cell response to Mycobacterium tuberculosis DosR and Rpf antigens in a Colombian population of household contacts of recently diagnosed pulmonary tuberculosis patients.
Tuberculosis (Edinburgh, Scotland) - 1 Mar 2016
Arroyo Leonar, Rojas Mauricio, Ortíz Blanca L, Franken Kees L M C, García Luis F, Ottenhoff Tom H M, Barrera Luis F
Abstract excerpt
Immune response to DosR and Rpf antigens from Mycobacterium tuberculosis (Mtb) seems to be important for latency maintenance. Little is known about the dynamics of the immune response to these antigens in an endemic community. Thus, the IFNγ response and cytokine production in response to PPD, Esat6-Cfp10 (E6-C10), DosR and Rpf antigens in healthy HHC of tuberculosis (TB) patients over a 12 (T12) months period...
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