Mutational Landmarks in Anaplastic Thyroid Cancer: A Perspective of a New Treatment Strategy

Abstract excerpt

Anaplastic thyroid carcinoma (ATC) is the rarest and most aggressive form of thyroid cancer, marked by a poor prognosis and resistance to conventional treatments. Like many malignancies, ATC has a complex genetic landscape, with numerous mutations driving tumor initiation, progression, and therapeutic resistance. However, recent advances in molecular research have expanded our understanding of these genetic altera...

Topics

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• MAP Kinase Signaling System
• Molecular Targeted Therapy
• Mutation
• Protein Kinase Inhibitors
• Proto-Oncogene Proteins B-raf
• Thyroid Cancer Diagnosis and Treatment
• Thyroid Carcinoma, Anaplastic
• Thyroid Neoplasms

Identifiers and source

Literature Corpus work

c502e62a-1c9e-5b47-ad3c-6102f33a485f

DOI

10.20944/preprints202503.1312.v1