Article
Association of G22A and A4223C ADA1 gene polymorphisms and ADA activity with PCOS.
Systems biology in reproductive medicine - 1 Jun 2016
Salehabadi Mahshid, Farimani Marzieh, Tavilani Heidar, Ghorbani Marzieh, Poormonsefi Faranak, Poorolajal Jalal, Shafiei Gholamreza, Ghasemkhani Neda, Khodadadi Iraj
Abstract excerpt
Adenosine deaminase-1 (ADA1) regulates the concentration of adenosine as the main modulator of oocyte maturation. There is compelling evidence for the association of ADA1 gene polymorphisms with many diseases but the importance of ADA1 polymorphisms in polycystic ovary syndrome (PCOS) has not been studied before. This study investigates serum total ADA activity (tADA), ADA1 and ADA2 isoenzyme activities, and...
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