Article
Association study for single nucleotide polymorphisms in the CYP17A1 gene and polycystic ovary syndrome.
International journal of molecular medicine - 1 Aug 2008
Park Jung-Mi, Lee Eung-Ji, Ramakrishna Suresh, Cha Dong-Hyun, Baek Kwang-Hyun
Abstract excerpt
Women with polycystic ovary syndrome (PCOS) are characterized by excess androgen secretion and anovulatory infertility as a cause of follicular maturation arrest, and they are also associated with insulin resistance and obesity. Recently, it was suggested that one of the etiologies for PCOS is an abnormality of steroid hormones, and excessive secretion of androgen. The endoplasmic reticular cytochrome P450,...
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