Article
Distribution of HLA DRB1 and DQB1 alleles and DRB1-DQB1 haplotypes among Bahraini women with polycystic ovary syndrome.
Journal of reproductive immunology - 1 Sept 2016
Messadi Amira, Malalla Zainab H, Al-Madhi Safa A, Al-Jalahma Jawaher A, Almawi Wassim Y
Abstract excerpt
OBJECTIVE: This study investigated the association between HLA-DRB1 and -DQB1 alleles and DRB1-DQB1 haplotypes, and polycystic ovary syndrome (PCOS) in Bahraini women. DESIGN: Case-control, retrospective study. METHODS: Study subjects comprised 80 women with PCOS, and 169 age- and ethnically-matched control women. DRB1 and DQB1 genotyping was done by PCR-SSP. RESULTS: Of the 13 DRB1 alleles and 5 DQB1 alleles...
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