Article
Genetic variations in the 3'-untranslated region of SLC18A2 are associated with serum FSH concentration in polycystic ovary syndrome patients and regulate gene expression in vitro.
Human reproduction (Oxford, England) - 1 Sept 2016
Li Qiaoli, Yan Zheng, Kuang Yanping, Zhou Xinyao, Jin Li, He Lin, Sun Xiaoxi, Tao Tao, Wang Lei
Abstract excerpt
STUDY QUESTION: Are genetic variations at the human solute carrier family 18 member A2 (SLC18A2) locus associated with the etiology of polycystic ovary syndrome (PCOS) and/or with follicle stimulating hormone (FSH) levels and insulin secretion in PCOS? SUMMARY ANSWER: We found two common genetic variants in the 3'-untranslated region of SLC18A2 (rs363282 and rs363238) that are associated with serum FSH...
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