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Article

The Association Between WAVE1 and -3 and the ARP2/3 Complex in PC 3 Cells.

Anticancer research - 1 Mar 2016

Weeks Hoi Ping, Sanders Andrew J, Kynaston Howard G, Jiang Wen G

Abstract excerpt

BACKGROUND: Actin polymerisation is stimulated by the actin-related protein (ARP) 2/3 complex and drives cell migration. This complex is activated by Wiskott-Aldrich syndrome protein family (WASP) verprolin homologous protein (WAVE) proteins. WAVE1 and -3 have been implicated in the aggressiveness of metastatic prostate cancer cells. MATERIALS AND METHODS: Cell growth, motility and invasion were analyzed in...

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PMID: 26977009

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