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Article

Essential requirement for Rho family GTPase signaling in Pax3 induced mesenchymal-epithelial transition.

Cellular signalling - 1 Sept 2006

Wiggan O'Neil, Shaw Alisa E, Bamburg James R

Abstract excerpt

We previously showed that the transcription factor Pax3 regulates mesenchymal-to-epithelial transition (MET) in cultured osteogenic Saos-2 cells. Herein we demonstrate that Pax3 induced MET in these cells requires intact Pax3 DNA binding motifs and is associated with the altered expression and ac...

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Source

Identifiers

PMID: 16442263
DOI: 10.1016/j.cellsig.2005.12.002

Genes

MET
PAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16442263-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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