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Article

Pharmacogenetics of ABCB5, ABCC5 and RLIP76 and doxorubicin pharmacokinetics in Asian breast cancer patients.

The pharmacogenomics journal - 1 Jul 2017

Lal S, Sutiman N, Ooi L L, Wong Z W, Wong N S, Ang P C S, Chowbay B

Abstract excerpt

This study investigated the impact of ABCB5, ABCC5 and RLIP76 polymorphisms on doxorubicin pharmacokinetics in Asian breast cancer patients (N=62). Direct sequencing was performed to screen for previously identified ABCC5 polymorphisms as well as polymorphisms in the exons and exon-intron boundaries of ABCB5 and RLIP76 genes. Genotype-phenotype correlations were analyzed using Mann-Whitney U-test. The homozygous...

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Source

Identifiers

PMID: 26975227
DOI: 10.1038/tpj.2016.17

Genes

ABCC5
ABCB5

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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