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Pharmacogenetics of Target Genes Across Doxorubicin Disposition Pathway: A Review

1 Jan 2010

Abstract excerpt

Increased understanding of the molecular mechanisms of tumor heterogeneity combined with rapid advances in the field of pharmacogenetics and pharmacogenomics have fuelled studies on individualizing anticancer therapy. Doxorubicin (Adriamycin), is an anthracycline glycoside antibiotic originally produced by Streptomyces peucetius var. caesius, and is widely used either as a single agent or in combination with...

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PMID: 20302569
DOI: 10.2174/138920010791110890

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