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Article

Promiscuous Recognition of a Trypanosoma cruzi CD8+ T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients.

PloS one - 1 Jan 2016

Lasso Paola, Beltrán Lina, Guzmán Fanny, Rosas Fernando, Thomas M Carmen, López Manuel Carlos, González John Mario, Cuéllar Adriana, Puerta Concepción J

Abstract excerpt

BACKGROUND: TcTLE is a nonamer peptide from Trypanosoma cruzi KMP-11 protein that is conserved among different parasite strains and that is presented by different HLA-A molecules from the A2 supertype. Because peptides presented by several major histocompatibility complex (MHC) supertypes are potential targets for immunotherapy, the aim of this study was to determine whether MHC molecules other than the A2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Epitopes, T-Lymphocyte

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Identifiers

PMID: 26974162
DOI: 10.1371/journal.pone.0150996
PMCID: PMC4790940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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