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Article

Exploring isoxazole and carboxamide derivatives as potential non-nucleoside reverse transcriptase inhibitors.

Journal of molecular graphics & modelling - 1 Apr 2016

Kurup Sudheer S, Joshi Kaustubh A

Abstract excerpt

Nonnucleoside reverse transciptase inhibitors (NNRTI) are a class of drug molecules with a specific target of HIV-1 reverse transcriptase (RT). In the present work, we evaluated a set of selected oxazole and carboxamide derivatives to identify potential pharmacophoric features using molecular docking approach. The docking approach employed has been validated by enrichment factor calculation at top 1% (EF1%). It...

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Identifiers

PMID: 26973048
DOI: 10.1016/j.jmgm.2016.02.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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