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Article

Activity and molecular modeling of a new small molecule active against NNRTI-resistant HIV-1 mutants.

European journal of medicinal chemistry - 1 Dec 2009

Carta Antonio, Pricl Sabrina, Piras Sandra, Fermeglia Maurizio, La Colla Paolo, Loddo Roberta

Abstract excerpt

In this preliminary study we report the antiviral screening of triazolo[4,5-g]quinoline derivatives (compounds 1-6). 4,9-Dihydrotriazolo[4,5-g]quinoline-1-oxide (1) stood out as a new, small molecule endowed with a selective, promising activity in cell-based assays against HIV-1wt and clinically...

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Source

Identifiers

PMID: 19775780
DOI: 10.1016/j.ejmech.2009.08.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19775780-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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