Article
Meta-analysis of genome-wide association studies reveals genetic overlap between Hodgkin lymphoma and multiple sclerosis.
International journal of epidemiology - 1 Jun 2016
Khankhanian Pouya, Cozen Wendy, Himmelstein Daniel S, Madireddy Lohith, Din Lennox, van den Berg Anke, Matsushita Takuya, Glaser Sally L, Moré Jayaji M, Smedby Karin E, Baranzini Sergio E, Mack Thomas M, Lizée Antoine, de Sanjosé Silvia, Gourraud Pierre-Antoine, Nieters Alexandra, Hauser Stephen L, Cocco Pierluigi, Maynadié Marc, Foretová Lenka, Staines Anthony, Delahaye-Sourdeix Manon, Li Dalin, Bhatia Smita, Melbye Mads, Onel Kenan, Jarrett Ruth, McKay James D, Oksenberg Jorge R, Hjalgrim Henrik
Abstract excerpt
BACKGROUND: Based on epidemiological commonalities, multiple sclerosis (MS) and Hodgkin lymphoma (HL), two clinically distinct conditions, have long been suspected to be aetiologically related. MS and HL occur in roughly the same age groups, both are associated with Epstein-Barr virus infection and ultraviolet (UV) light exposure, and they cluster mutually in families (though not in individuals). We speculated if...
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