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Article

Common pathways regulate Type III TGFβ receptor-dependent cell invasion in epicardial and endocardial cells.

Cellular signalling - 1 Jun 2016

Clark Cynthia R, Robinson Jamille Y, Sanchez Nora S, Townsend Todd A, Arrieta Julian A, Merryman W David, Trykall David Z, Olivey Harold E, Hong Charles C, Barnett Joey V

Abstract excerpt

Epithelial-Mesenchymal Transformation (EMT) and the subsequent invasion of epicardial and endocardial cells during cardiac development is critical to the development of the coronary vessels and heart valves. The transformed cells give rise to cardiac fibroblasts and vascular smooth muscle cells or valvular interstitial cells, respectively. The Type III Transforming Growth Factor β (TGFβR3) receptor regulates EMT...

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Identifiers

PMID: 26970186
DOI: 10.1016/j.cellsig.2016.03.004
PMCID: PMC4827451

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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