Article
A Longitudinal Study ofBDNFPromoter Methylation and Depression in Breast Cancer
1 Jan 2015
Abstract excerpt
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) is investigated in depression related to medical disorders and its secretion is influenced by epigenetic factors. We investigated the association between BDNF promoter methylation and depression following mastectomy for breast cancer. METHODS: In total, 309 patients with breast cancer were evaluated 1 week after mastectomy, and 244 (79%) were followed up 1 year...
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