Article
[Gene mutations connected to Waldenstöm macroglobulinemia].
Vnitrni lekarstvi - 1 Jan 2016
Kutálková Kateřina, Sedlaříková Lenka, Adam Zdeněk, Ševčíková Sabina
Abstract excerpt
Waldenstöm macroglobulinemia (WM) is a rare lymphoproliferative disorder, currently classified as a monoclonal gammopathy, with incidence rate of 3 per million. The disease is characterized by presence of clonal B lymphocytes in the bone marrow and by presence of monoclonal immunoglobulin IgM in serum. It is mostly an indolent disorder, with median overall survival 6 years. Molecular pathogenesis of WM remains...
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