Article
[New developments in Waldenström's macroglobulinemia].
Deutsche medizinische Wochenschrift (1946) - 1 Feb 2016
Grunenberg Alexander, Buske Christian
Abstract excerpt
Waldenström's Macroglobulinemia (WM) is a rare subtype of B-cell lymphoma with mostly indolent course. Until now the backbone of therapy is still Rituximab / Chemotherapy. In recent years whole genome sequencing has revealed a number of genetic mutations, among them mutations of the MYD88 gene which occurs in over 90 % of patients and helps to validate diagnosis of WM in difficult cases. With the introduction of...
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