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Article

ACSL4 promotes malignant progression of Hepatocellular carcinoma by targeting PAK2 transcription

12 Apr 2024

Abstract excerpt

Long-chain fatty acyl-Coa ligase 4 (ACSL4) is an important enzyme that converts fatty acids to fatty acyl-Coa esters, there is increasing evidence for its role in carcinogenesis. However, the precise role of ACLS4 in hepatocellular carcinoma (HCC) is not clearly understood. In the present study, we provide evidence that ACSL4 expression was specifically elevated in HCC and is associated with poor clinical...

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Identifiers

PMID: 38615921
DOI: 10.1016/j.bcp.2024.116206

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