Article
Heterogeneity and individuality: microRNAs in mental disorders.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2015
Hommers Leif G, Domschke Katharina, Deckert Jürgen
Abstract excerpt
MicroRNAs are about 22 nucleotide long single-stranded RNA molecules, negatively regulating gene expression of a single gene or a gene network. In neural tissues, they have been implicated in developmental and neuroplasticity-related processes, such as neurogenesis, differentiation, apoptosis and long-term potentiation. Their molecular mode of action is reminiscent of findings of genome-wide association studies...
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