Article
Intrinsic phenotypic stability of a bi-stable auto regulatory gene.
Scientific reports - 10 Mar 2016
Besya Azim-Berdy, Grönlund Andreas
Abstract excerpt
Even under homogenous conditions clonal cells can assume different distinct states for generations to follow, also known as epigenetic inheritance. Such long periods of different phenotypic states can be formed due to the existence of more than one stable state in the molecule concentration, where the different states are explored through molecular fluctuations. By formulating a single reaction variable...
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