Article
Phenotypic variability of growing cellular populations.
Proceedings of the National Academy of Sciences of the United States of America - 27 Nov 2007
Lu Ting, Shen Tongye, Bennett Matthew R, Wolynes Peter G, Hasty Jeff
Abstract excerpt
The dynamics and diversity of proliferating cellular populations are governed by the interplay between the growth and death rates among the various phenotypes within a colony. In addition, epigenetic multistability can cause cells to spontaneously switch from one phenotype to another. By examining a generalized form of the relative variance of populations and classifying it into intracolony and cross-colony...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
