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Article

Stochastic stabilization of phenotypic States: the genetic bistable switch as a case study.

PloS one - 1 Jan 2013

Weber Marc, Buceta Javier

Abstract excerpt

We study by means of analytical calculation and stochastic simulations how intrinsic noise modifies the bifurcation diagram of gene regulatory processes that can be effectively described by the Langevin formalism. In a general context, our study raises the intriguing question of how biochemical fluctuations redesign the epigenetic landscape in differentiation processes. We have applied our findings to a general...

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Identifiers

PMID: 24039958
DOI: 10.1371/journal.pone.0073487
PMCID: PMC3770683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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