Article
Mitochondria single nucleotide variation across six blood cell types.
Mitochondrion - 1 May 2016
Zhang Pan, Samuels David C, Wang Jing, Zhao Shilin, Shyr Yu, Guo Yan
Abstract excerpt
It has been shown that heteroplasmic mitochondrial DNA variants can be tissue specific. However, whether mitochondrial DNA variants are specific by blood cell types has not been investigated. Motivated by this question and using mitochondria sequences extracted from RNAseq data from six distinct blood cell types (neutrophil, monocyte, myeloid dendritic, natural killer, T and B), we thoroughly compared SNPs and...
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