Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In vitro selection of Staphylococcus aureus mutants resistant to tigecycline with intermediate susceptibility to vancomycin.

Annals of clinical microbiology and antimicrobials - 8 Mar 2016

Herrera Melina, Di Gregorio Sabrina, Fernandez Silvina, Posse Graciela, Mollerach Marta, Di Conza José

Abstract excerpt

BACKGROUND: Tigecycline (TIG) is an antibiotic belonging to the glycylcyclines class and appears to be a good choice to fight infections caused by Staphylococcus aureus. To date, TIG exhibits good activity against this microorganism. The aim of this work was to obtain in vitro mutants of S. aureus resistant to TIG and evaluate possible changes in their susceptibility patterns to other antibiotics. RESULTS: Two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microbial Sensitivity Tests

Share to Minocycline

Share to Staphylococcal Infections

Share to Staphylococcus aureus

Share to Tigecycline

Share to Vancomycin

Source

Open in PubMed Open full text

Identifiers

PMID: 26956508
DOI: 10.1186/s12941-016-0131-7
PMCID: PMC4782574

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In vitro selection of Staphylococcus aureus mutants resistant to tigecycline with intermediate susceptibility to vancomycin.PMID 26956508Read ↗

Genetic changes associated with tigecycline resistance in Staphylococcus aureus in vitro-selected mutants belonging to different lineages.Semantic proximity Read ↗

Mutations in the MepRAB efflux system contribute to the in vitro development of tigecycline resistance in Staphylococcus aureus.Semantic proximity Read ↗

Resistance in In Vitro Selected Tigecycline-Resistant Methicillin-Resistant Staphylococcus aureus Sequence Type 5 Is Driven by Mutations in mepR and mepA Genes.Semantic proximity Read ↗

Comparative time-kill study of doxycycline, tigecycline, cefazolin and vancomycin against several clones of Staphylococcus aureus.Semantic proximity Read ↗

Genomic analysis of reduced susceptibility to tigecycline in Enterococcus faecium.Semantic proximity Read ↗

Tigecycline and inducible clindamycin resistance in clinical isolates of methicillin-resistant Staphylococcus aureus from Terengganu, MalaysiaSemantic proximity Read ↗

Characteristics of French methicillin-resistant Staphylococcus aureus isolates with decreased susceptibility or resistance to glycopeptides.Semantic proximity Read ↗

Phenotypic and genotypic changes of Staphylococcus aureus in the presence of the inappropriate concentration of chlorhexidine gluconate.Semantic proximity Read ↗

A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline.Semantic proximity Read ↗

Interaction of the GraRS Two-Component System with the VraFG ABC Transporter To Support Vancomycin-Intermediate Resistance in <i>Staphylococcus aureus</i>Semantic proximity Read ↗

Tigecycline Resistance-Associated Mutations in the MepA Efflux Pump in Staphylococcus aureus.Semantic proximity Read ↗

First description of rpsJ and mepA mutations associated with tigecycline resistance in Staphylococcus aureus isolated from a cystic fibrosis patient during antibiotic therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.