Article

FLNC and MYLK2 gene mutations in a Chinese family with different phenotypes of cardiomyopathy

2020-05-11

Abstract excerpt

<title>Abstract</title> <p>Background Mutations in the sarcomeric protein filamin C (<italic>FLNC</italic>) gene have been linked to hypertrophic cardiomyopathy (HCM), in which they increase the risk of ventricular arrhythmia and sudden death. In this study, we identified a novel missense mutation of <italic>FLNC</italic> in a Chinese family with HCM and interestingly a second novel truncating mutation of <itali...

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Identifiers and source

Literature Corpus work: 58ee0735-dcf5-5243-a733-a0d8ea8fae6e
DOI: 10.21203/rs.3.rs-26973/v1

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