Article
Semaphorin and Eph receptor signaling guide a series of cell movements for ventral enclosure in C. elegans.
Current biology : CB - 10 Jan 2012
Ikegami Richard, Simokat Kristin, Zheng Hong, Brown Louise, Garriga Gian, Hardin Jeff, Culotti Joseph
Abstract excerpt
BACKGROUND: In the last stage of the Caenorhabditis elegans body wall closure, an open pocket in the epidermis is closed by the migration of marginal epidermal P/pocket cells to the ventral midline. The cellular and molecular mechanisms of this closure remain unknown. RESULTS: Cells within the pocket align to form a bridge for migration of contralateral P cell pair P9/10 L,R (and neighboring P cells) to the...
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