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Article

Ciprofloxacin mediates cancer stem cell phenotypes in lung cancer cells through caveolin-1-dependent mechanism.

Chemico-biological interactions - 25 Apr 2016

Phiboonchaiyanan Preeyaporn Plaimee, Kiratipaiboon Chayanin, Chanvorachote Pithi

Abstract excerpt

Cancer stem cells (CSCs), a subpopulation of cancer cells with high aggressive behaviors, have been identified in many types of cancer including lung cancer as one of the key mediators driving cancer progression and metastasis. Here, we have reported for the first time that ciprofloxacin (CIP), a widely used anti-microbial drug, has a potentiating effect on CSC-like features in human non-small cell lung cancer...

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Identifiers

PMID: 26947806
DOI: 10.1016/j.cbi.2016.03.005

Genes

ABCG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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