Article
Finding the right coverage: the impact of coverage and sequence quality on single nucleotide polymorphism genotyping error rates.
Molecular ecology resources - 1 Jul 2016
Fountain Emily D, Pauli Jonathan N, Reid Brendan N, Palsbøll Per J, Peery M Zachariah
Abstract excerpt
Restriction-enzyme-based sequencing methods enable the genotyping of thousands of single nucleotide polymorphism (SNP) loci in nonmodel organisms. However, in contrast to traditional genetic markers, genotyping error rates in SNPs derived from restriction-enzyme-based methods remain largely unknown. Here, we estimated genotyping error rates in SNPs genotyped with double digest RAD sequencing from Mendelian...
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