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Optimized double-digest genotyping by sequencing (ddGBS) method with high-density SNP markers and high genotyping accuracy for chickens.

PloS one - 1 Jan 2017

Wang Yuzhe, Cao Xuemin, Zhao Yiqiang, Fei Jing, Hu Xiaoxiang, Li Ning

Abstract excerpt

High-density single nucleotide polymorphism (SNP) markers are crucial to improve the resolution and accuracy of genome-wide association study (GWAS) and genomic selection (GS). Numerous approaches, including whole genome sequencing, genome sampling sequencing, and SNP chips are able to discover or genotype markers at different densities and costs. Achieving an optimal balance between sequencing resolution and...

Topics

Animals
Chickens
Computational Biology
Genotype
Genotyping Techniques
High-Throughput Nucleotide Sequencing
Polymorphism, Single Nucleotide
Reproducibility of Results

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28598985
DOI: 10.1371/journal.pone.0179073
PMCID: PMC5466311

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