Article
Complement factor H and susceptibility to major depressive disorder in Han Chinese.
The British journal of psychiatry : the journal of mental science - 1 May 2016
Zhang Chen, Zhang Deng-Feng, Wu Zhi-Guo, Peng Dai-Hui, Chen Jun, Ni Jianliang, Tang Wenxin, Xu Lin, Yao Yong-Gang, Fang Yi-Ru
Abstract excerpt
BACKGROUND: Accumulating evidence suggests that altered immunity contributes to the development of major depressive disorder (MDD). AIMS: To examine whether complement factor H (CFH), a regulator of activation of the alternative pathway of the complement cascade, confers susceptibility to MDD. METHOD: Expression analyses were tested in 53 unmedicated people with MDD and 55 healthy controls. A two-stage genetic...
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