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Identification of TNFA influencing MDD risk and clinical features in Han Chinese.

Cytokine - 1 May 2020

Zhao Junxiong, Hua Shen, Wang Weiping, Fan Weixing, Tang Wei, Zhang Yi, Zhang Chen

Abstract excerpt

OBJECTIVE: Our recent genetic-neuroimaging study observed that the rs1799724 polymorphism within the TNFA gene encoding TNF-α selectively affects the anatomy of visual cortex in patients with MDD. In this study, we hypothesized that TNFA is risk factor to MDD, and TNFA rs1799724 polymorphism may be a susceptibility locus for this disorder and its clinical features. METHODS: We enrolled 807 MDD samples and 822...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32050144
DOI: 10.1016/j.cyto.2020.155030

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