Article
GWASeq: targeted re-sequencing follow up to GWAS.
BMC genomics - 3 Mar 2016
Salomon Matthew P, Li Wai Lok Sibon, Edlund Christopher K, Morrison John, Fortini Barbara K, Win Aung Ko, Conti David V, Thomas Duncan C, Duggan David, Buchanan Daniel D, Jenkins Mark A, Hopper John L, Gallinger Steven, Le Marchand Loïc, Newcomb Polly A, Casey Graham, Marjoram Paul
Abstract excerpt
BACKGROUND: For the last decade the conceptual framework of the Genome-Wide Association Study (GWAS) has dominated the investigation of human disease and other complex traits. While GWAS have been successful in identifying a large number of variants associated with various phenotypes, the overall amount of heritability explained by these variants remains small. This raises the question of how best to follow up on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.