Article
MIRU-VNTR Genotyping of Mycobacterium tuberculosis Strains Using QIAxcel Technology: A Multicentre Evaluation Study.
PloS one - 1 Jan 2016
Nikolayevskyy Vladyslav, Trovato Alberto, Broda Agnieszka, Borroni Emanuele, Cirillo Daniela, Drobniewski Francis
Abstract excerpt
BACKGROUND: Molecular genotyping of M.tuberculosis is an important laboratory tool in the context of emerging drug resistant TB. The standard 24-loci MIRU-VNTR typing includes PCR amplification followed by the detection and sizing of PCR fragments using capillary electrophoresis on automated sequencers or using agarose gels. The QIAxcel Advanced system might offer a cost-effective medium-throughput alternative....
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