Article
Quantifying and Mitigating the Effect of Preferential Sampling on Phylodynamic Inference.
PLoS computational biology - 1 Mar 2016
Karcher Michael D, Palacios Julia A, Bedford Trevor, Suchard Marc A, Minin Vladimir N
Abstract excerpt
Phylodynamics seeks to estimate effective population size fluctuations from molecular sequences of individuals sampled from a population of interest. One way to accomplish this task formulates an observed sequence data likelihood exploiting a coalescent model for the sampled individuals' genealogy and then integrating over all possible genealogies via Monte Carlo or, less efficiently, by conditioning on one...
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