Article
A method for accurate inference of population size from serially sampled genealogies distorted by selection.
Molecular biology and evolution - 1 Nov 2011
O'Fallon Brendan D
Abstract excerpt
The serial coalescent extends traditional coalescent theory to include genealogies in which not all individuals were sampled at the same time. Inference in this framework is powerful because population size and evolutionary rate may be estimated independently. However, when the sequences in question are affected by selection acting at many sites, the genealogies may differ significantly from their neutral...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
