Article
Slow Muscle Precursors Lay Down a Collagen XV Matrix Fingerprint to Guide Motor Axon Navigation.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Mar 2016
Guillon Emilie, Bretaud Sandrine, Ruggiero Florence
Abstract excerpt
The extracellular matrix (ECM) provides local positional information to guide motoneuron axons toward their muscle target. Collagen XV is a basement membrane component mainly expressed in skeletal muscle. We have identified two zebrafish paralogs of the human COL15A1 gene, col15a1a and col15a1b, which display distinct expression patterns. Here we show that col15a1b is expressed and deposited in the motor path ECM...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.