Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation.

Cell reports - 29 Oct 2019

Oprişoreanu Ana-Maria, Smith Hannah L, Arya Sukrat, Webster Richard, Zhong Zhen, Eaton-Hart Charlotte, Wehner Daniel, Cardozo Marcos J, Becker Thomas, Talbot Kevin, Becker Catherina G

Abstract excerpt

Chondrolectin (Chodl) is needed for motor axon extension in zebrafish and is dysregulated in mouse models of spinal muscular atrophy (SMA). However, the mechanistic basis of Chodl function is not known. Here, we use Chodl-deficient zebrafish and mouse mutants to show that the absence of Chodl leads to anatomical and functional defects of the neuromuscular synapse. In zebrafish, the growth of an identified motor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Electrophysiological Phenomena
Share to Escape Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lectins, C-Type

Share to Motor Neurons

Share to Neurites

Share to Neurogenesis

Share to Neuromuscular Junction

Share to Synapses

Source

Identifiers

PMID: 31665626
DOI: 10.1016/j.celrep.2019.09.033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation.PMID 31665626Read ↗

Chondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophySemantic proximity Read ↗

Collagen XIXa1 is crucial for motor axon navigation at intermediate targets.Semantic proximity Read ↗

Neuromuscular synaptogenesis in wild-type and mutant zebrafish.Semantic proximity Read ↗

Automated in vivo drug screen in zebrafish identifies synapse-stabilising drugs with relevance to spinal muscular atrophy.Semantic proximity Read ↗

The myotendinous junction marker collagen XXII enables zebrafish postural control learning and optimal swimming performance through its force transmission activitySemantic proximity Read ↗

The synaptic receptor Lrp4 promotes peripheral nerve regeneration.Semantic proximity Read ↗

Neuromuscular Development and Disease: Learning From in vitro and in vivo ModelsSemantic proximity Read ↗

A Laminin G-EGF-Laminin G module in Neurexin IV is essential for the apico-lateral localization of Contactin and organization of septate junctions.Semantic proximity Read ↗

Loss of thrombospondin reveals a possible role for the extracellular matrix in chordotonal cap cell elongation.Semantic proximity Read ↗

The zebrafish diwanka gene controls an early step of motor growth cone migration.Semantic proximity Read ↗

Regeneration of spinal motor axons: Negative regulation by Celsr2 implicating Cdc42/Rac1 and JNK/c-Jun signalingSemantic proximity Read ↗

Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.