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Article

Experimental Evolution Reveals Favored Adaptive Routes to Cell Aggregation in Yeast.

Genetics - 1 Jun 2017

Hope Elyse A, Amorosi Clara J, Miller Aaron W, Dang Kolena, Heil Caiti Smukowski, Dunham Maitreya J

Abstract excerpt

Yeast flocculation is a community-building cell aggregation trait that is an important mechanism of stress resistance and a useful phenotype for brewers; however, it is also a nuisance in many industrial processes, in clinical settings, and in the laboratory. Chemostat-based evolution experiments are impaired by inadvertent selection for aggregation, which we observe in 35% of populations. These populations...

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Identifiers

PMID: 28450459
DOI: 10.1534/genetics.116.198895
PMCID: PMC5499169

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