Article
High-Molecular-Weight β-Glucan Decreases Serum Cholesterol Differentially Based on the CYP7A1 rs3808607 Polymorphism in Mildly Hypercholesterolemic Adults.
The Journal of nutrition - 1 Apr 2016
Wang Yanan, Harding Scott V, Eck Peter, Thandapilly Sijo J, Gamel Tamer H, Abdel-Aal El-Sayed M, Crow Gary H, Tosh Susan M, Jones Peter Jh, Ames Nancy P
Abstract excerpt
BACKGROUND: β-Glucan, a soluble fiber with viscous property, has a documented cholesterol-lowering effect. The molecular weight (MW) of β-glucan, which contributes to viscosity, and an individual's genotype might influence the cholesterol-lowering efficacy of β-glucan. OBJECTIVES: This study was designed to determine whether the cholesterol-lowering efficacy of barley β-glucan varied as a function of MW and the...
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