Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Forced expression of Nanog with mRNA synthesized in vitro to evaluate the malignancy of HeLa cells through acquiring cancer stem cell phenotypes.

Oncology reports - 1 May 2016

Ding Yan, Yu Ai Qing, Wang Xiao Li, Guo Xing Rong, Yuan Ya Hong, Li Dong Sheng

Abstract excerpt

Nanog is a pluripotency-related factor. It was also found to play an important role in tumorigenesis. To date, the mechanisms underlying cervical tumorigenesis still need to be elucidated. In the present study, Nanog mRNA was synthesized in vitro and transfected into HeLa cells. After mRNA transfection, the forced expressed of Nanog in HeLa cells led to markedly increased invasion, migration, resistance to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Transformation, Neoplastic
Share to Cisplatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Nude

Share to Nanog Homeobox Protein

Share to Neoplasm Transplantation

Share to Neoplastic Stem Cells

Share to Paclitaxel

Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 26936116
DOI: 10.3892/or.2016.4639

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Forced expression of Nanog with mRNA synthesized in vitro to evaluate the malignancy of HeLa cells through acquiring cancer stem cell phenotypes.PMID 26936116Read ↗

TALEN-mediated Nanog disruption results in less invasiveness, more chemosensitivity and reversal of EMT in Hela cells.Semantic proximity Read ↗

Concise Review: NANOG in Cancer Stem Cells and Tumor Development: An Update and Outstanding QuestionsSemantic proximity Read ↗

Targeting cancer stem cells: emerging role of Nanog transcription factorSemantic proximity Read ↗

NANOG Promotes Cell Proliferation, Invasion, and Stemness via IL-6/STAT3 Signaling in Esophageal Squamous CarcinomaSemantic proximity Read ↗

ERK1/2-Nanog signaling pathway enhances CD44(+) cancer stem-like cell phenotypes and epithelial-to-mesenchymal transition in head and neck squamous cell carcinomas.Semantic proximity Read ↗

Expression of the Stem Cell Marker, Nanog, in Human Endometrial AdenocarcinomaSemantic proximity Read ↗

Regulation of NANOG in cancer cellsSemantic proximity Read ↗

Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancerSemantic proximity Read ↗

Insights into the Nanog gene: A propeller for stemness in primitive stem cellsSemantic proximity Read ↗

Doxycycline Induces Apoptosis and Inhibits Proliferation and Invasion of Human Cervical Carcinoma Stem CellsSemantic proximity Read ↗

NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cellsSemantic proximity Read ↗

Involvement of NANOG upregulation in malignant progression of human cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.