Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Involvement of NANOG upregulation in malignant progression of human cells.

DNA and cell biology - 1 Mar 2013

Li Yang, Higashiyama Shinji, Shimakage Misuzu, Kawahara Kunimitsu, Yutsudo Masuo, Watari Akihiro

Abstract excerpt

Previously, we isolated cell lines that display various degrees of transformed phenotypes from a single-cell population of human diploid fibroblasts (RB) containing a large deletion (13q14-22) in one copy of chromosome 13. They included a cell line transfected with SV40 early genes (RBSV), an immortalized cell line (RBI), an anchorage-independent cell line (RBS), and a tumorigenic cell line (RBT). Here, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Adenocarcinoma of Lung
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 13

Share to Fibroblasts

Share to Homeodomain Proteins

Share to Nanog Homeobox Protein

Share to Up-Regulation

Source

Identifiers

PMID: 23427894
DOI: 10.1089/dna.2012.1908

Genes

NANOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Involvement of NANOG upregulation in malignant progression of human cells.PMID 23427894Read ↗

Malignant transformation of 293 cells induced by ectopic expression of human NanogSemantic proximity Read ↗

Concise Review: NANOG in Cancer Stem Cells and Tumor Development: An Update and Outstanding QuestionsSemantic proximity Read ↗

Regulation of NANOG in cancer cellsSemantic proximity Read ↗

Prognostic significance of NANOG expression in solid tumors: a meta-analysisSemantic proximity Read ↗

Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cellsSemantic proximity Read ↗

Insights into the Nanog gene: A propeller for stemness in primitive stem cellsSemantic proximity Read ↗

Targeting cancer stem cells: emerging role of Nanog transcription factorSemantic proximity Read ↗

Functional Evidence that the Self-Renewal Gene <i>NANOG</i> Regulates Human Tumor DevelopmentSemantic proximity Read ↗

The oncogenic potential of NANOG: An important cancer induction mediatorSemantic proximity Read ↗

Increased Nanog Expression Promotes Tumor Development and Cisplatin Resistance in Human Esophageal Cancer CellsSemantic proximity Read ↗

ERK1/2-Nanog signaling pathway enhances CD44(+) cancer stem-like cell phenotypes and epithelial-to-mesenchymal transition in head and neck squamous cell carcinomas.Semantic proximity Read ↗

NANOG: A promising target for digestive malignant tumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.