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Article

Persistent polyclonal binucleated B-cell lymphocytosis and MECOM gene amplification.

BMC research notes - 2 Mar 2016

Cornet Edouard, Mossafa Hossein, Courel Karine, Lesesve Jean-François, Troussard Xavier

Abstract excerpt

BACKGROUND: Persistent Polyclonal Binucleated B-cell Lymphocytosis (PPBL) is characterized by a chronic polyclonal B-cell lymphocytosis with binucleated lymphocytes and a polyclonal increase in serum immunoglobulin-M. Cytogenetic is characterized by the presence of a supernumerary isochromosome +i(3)(q10), premature chromosome condensation and chromosomal instability. Outcome of PPBL patients is mostly benign,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26935937
DOI: 10.1186/s13104-015-1742-3
PMCID: PMC4776409

Genes

MECOM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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