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Article

Timing of acquisition of deletion 13 in plasma cell dyscrasias is dependent on genetic context

1 Dec 2009

Abstract excerpt

BACKGROUND: Multiple myeloma, monoclonal gammopathy of undetermined significance and smoldering multiple myeloma harbor common chromosomal abnormalities but the prevalence and relative association of aberrations in these diagnostic groups remains controversial. We investigated these aspects in a large series of patients. DESIGN AND METHODS: Chromosome 13 deletion (Delta13), deletion of TP53, ploidy status and...

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PMID: 19996118
DOI: 10.3324/haematol.2009.011064

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