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Genomic abnormalities in monoclonal gammopathy of undetermined significance

15 Aug 2002

Abstract excerpt

Translocations involving immunoglobulin (Ig) loci and chromosome 13 monosomy (Delta 13) are frequent cytogenetic findings in multiple myeloma (MM). Similar chromosomal aberrations have been identified in the monoclonal gammopathy of undetermined significance (MGUS), but their prevalence and significance remain uncertain. Bone marrow from 72 patients with MGUS (n = 62) and smoldering MM (n = 10) was evaluated for...

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Identifiers

PMID: 12149226
DOI: 10.1182/blood.v100.4.1417.h81602001417_1417_1424

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Source receipt: pubmed, retrieved 7 Sept 2026.

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