Article
Cold agglutinin–associated B-cell lymphoproliferative disease shows highly recurrent gains of chromosome 3 and 12 or 18
13 Mar 2020
Abstract excerpt
Primary cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia caused by a distinct type of B-cell lymphoproliferative disease of the bone marrow. We have recently evaluated the use of bendamustine-rituximab therapy for CAD and found that B cell-directed therapy is highly efficient and safe and may be considered first line therapy for relatively fit patients with CAD. Immunoglobulins are almost...
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