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Article

Evidence for ACTN3 as a Speed Gene in Isolated Human Muscle Fibers.

PloS one - 1 Jan 2016

Broos Siacia, Malisoux Laurent, Theisen Daniel, van Thienen Ruud, Ramaekers Monique, Jamart Cécile, Deldicque Louise, Thomis Martine A, Francaux Marc

Abstract excerpt

PURPOSE: To examine the effect of α-actinin-3 deficiency due to homozygosity for the ACTN3 577X-allele on contractile and morphological properties of fast muscle fibers in non-athletic young men. METHODS: A biopsy was taken from the vastus lateralis of 4 RR and 4 XX individuals to test for differences in morphologic and contractile properties of single muscle fibers. The cross-sectional area of the fiber and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26930663
DOI: 10.1371/journal.pone.0150594
PMCID: PMC4773019

Genes

ACTN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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Alpha-actinin-3 deficiency does not significantly alter oxidative enzyme activity in fast human muscle fibres.Semantic proximity Read ↗

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